The second edition of An Inquiry into the Causes and Effects of the Variolae Vaccinae by Edward Jenner published in 1800 is an English rare book examining Cow Pox, which led to the discovery of the first vaccine ever, in this case, for Small Pox. Physically, the book isn’t very heavy and measures around 27x22 cm. Its cover is made out of leather and a type of cardboard material and has black bindings with striped colors on it, mostly red accompanied with yellow and blue. The content of the book is written with a large and spaced-out font, and empty columns are present on each sides of the…